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| Product Name: |
Sarm Yk 11/Yk11 1379686-30-2 steroids powder
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| Supply Ability: |
800kg/week |
| Related proudcts |
steroids powder, 1379686-30-2, sarm yk 11, |
| Specifications |
1kg/bag |
| Price Term: |
FOB |
| Port of loading: |
SHENZHEN |
| Minimum Order |
10g |
| Unit Price: |
usd3/gram |
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What is YK11?
Full Name: (17-alpha,20E) 17,20-[(1-methoxyethylidene)bis(oxy)] 3-oxo-19-norpregna-4,20-diene 21-carboxylic acid methyl ester
Product Name: sarm yk11 1370003-76-1
Specification: �9%
Appearance: White fine Powder
Product Description
(17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11), which the myogenic differentiation of C2C12 myoblast cells is induced by the novel androgen receptor (AR) partial agonist. as well as by dihydrotestosterone (DHT).
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells. The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products. YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic growth properties of YK11
Fuction
It induces muscle cells to make more follistatin which is a strong |
| Company: |
Jinan Jia Ge Biological Technology Co.,LTD
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| Contact: |
Ms. Sally Zhang |
| Address: |
Room 1804, Unit 1, Building 19 |
| Postcode: |
266555 |
| Tel: |
86 17753110973 |
| Fax: |
86 17753110973 |
| E-mail: |
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